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What are the side effects of progesterone (Progest, Prometrium)?

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Progesterone (brand names Progest, Prometrium) is a drug that can be
used to treat infertility. Infertility is described as the inability
to conceive a baby within one year of trying.
Progesterone is a hormone that causes menstrual periods in women who
have not yet reached menopause but are not having periods due to a
lack of natural progesterone in the body. It can also be used to
maintain a pregnancy in women unable to produce enough progesterone
within their bodies to keep their pregnancy going.

Other uses of progesterone include prevention of endometrial
hyperplasia (thickening of the uterus lining), treatment of
endometriosis and associated pain, help in treatment of certain
cancers, treatment of severe weight loss in people with AIDS, and
prevention of pregnancy in very low doses.

The dose of progesterone varies widely from person to person and is
determined by the reason for treatment. Talk to your doctor about the
best dose for you. Be sure to take it exactly as your doctor
recommends.

Side effects of progesterone can include sudden headache or
confusion, vision problems, migraine headache, nausea, stomach pain,
breast lumps, vaginal bleeding, mood swings, bowel changes,
tiredness, runny nose, cough, and depression. Tell your doctor if
these side effects become bothersome or do not get better with time.
In rare cases, a person may experience chest pain, shortness of
breath, faintness, shaking, seizures, leg swelling or pain, and
sudden numbness or weakness on one side of the body. Be sure to
notify your doctor right away if you experience any of these serious
side effects.

If you are having difficulty becoming pregnant, be sure to talk to
your doctor about what the best treatment is for you.

Sources:
Drug Facts and Comparisons. Facts & Comparisons, 2007.Drugs and
Supplements, "Progestins-For noncontraceptive Use (Systemic)."
http://mayoclinic.com. Mayo Clinic Health. Last accessed 2/14/2007.
Medline Plus. Medline, 2007.Micromedex® Healthcare Series. Thomson
Micromedex, 2007.


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