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Dr.  Samuel Epstein's Scientific Articles

 

1. Epstein, S. S., and Winston, P. Intubation granuloma. J. Laryngol. Otol., 71:17-38, 1957.

2. Epstein, S. S., et al. The vocal cord polyp. J. Laryngol. Otol., 71:673-688, 1957.

3. Epstein, S. S. and Shaw, H. J. Metastatic cancer of the larynx as a cause of carotid-sinus syndrome. Cancer, 10:933-937, 1957.

4. Epstein, S. S. An intra-oral inoculation technique for the production of experimental pneumonia in mice. J. Hygiene, 56:73-79, 1958.

5. Epstein, S. S. and Stratton, K. Further studies on the mouse intra-oral inoculation technique. J. Hygiene, 56:81-83, 1958.

6. Epstein, S. S. and Shaw, H. J. Multiple malignant neoplasms in the air and upper food passages. Cancer, 11:326-333, 1958.

7. Winston, P. and Epstein, S. S. Papilloma of the larynx: A clinico-pathological study. J. Laryngol. Otol., 72:452-464, 1958.

8. Epstein, S. S. and Friedmann, I. Klebsiella serotypes in infections of the ear and upper respiratory tract. J. Clin. Path., 2:359-362, 1958.

9. Epstein, S. S. A "stripping" technique for the examination of the total epithelial surface of the larynx. J. Path. Bact., 75:472-473, 1958.

10. Freeman, T., Wakefield, G. S., and

Epstein, S. S. Platelet-agglutinating factor in glandular fever complicated by jaundice and thrombocytopenia. Lancet, 383-385, Oct. 25, 1958.

11. Epstein, S. S. and Bradbeer, T. L. A case of primary diptheritic otitis media. J. Laryngol. Otol., 72:1001-1003, 1958.

12. Epstein, S. S. Experimental Klebsiella pneumonia in mice with particular reference to periarterial changes. J. Path. Bact., 78:389-396, 1959.

13. Epstein, S. S. The biochemistry and antibiotic sensitivity of the Klebsiellae. J. Clin. Path., 12:52-58, 1959.

14. Epstein, S. S. and Payne, P. M. The effect of some variables on experimental Klebsiella infections in mice. J. Hygiene, 57:68-80, 1959.

15. Shaw, H. J. and Epstein, S. S. Cancer of the epiglottis. Cancer, 12:246-256, 1959.

16. Epstein, S. S. and Weiss, J. B. The extraction of pigments from Euglena gracilis. Biochem. J., 75:247-250, 1959.

17. Timmis, G. M. and Epstein, S. S. New antimetabolites of Vitamin B12. Nature, 184:1383-1384, 1959.

18. Epstein, S. S., et al. Multiple primary malignant neoplasms in the air and upper food passages. Cancer, 13:461-463, 1960.

19. Epstein, S. S. and Weiss, J. B. Measuring the size of isolated cells. Nature, 187:461-463, 1960.

20. Epstein, S. S. Effects of some benzimidazoles on a Vitamin B12-requiring alga. Nature, 188:143-144, 1960.

21. Epstein, S. S., et al. Vitamin B12 and growth of Euglena gracilis. Fed. Proc., 20(1):450, 1961.

22. Epstein, S. S. and Timmis, G. M. "Simple" Vitamin B12 antimetabolites. Proc. Amer. Assoc. Cancer Res., 3(3):223, 1961.

23. Epstein, S. S. and Burroughs, M. Some factors influencing the photodynamic response of Paramecium caudatum to 3,4-benzpyrene. Nature, 193:337-338, 1962.

24. Epstein, S. S., et al. The photodynamic toxicity of polycyclic hydrocarbons. Proc. Amer. Assoc. Cancer Res., 3(4):316, 1962.

25. Epstein, S. S., et al. Influence of Vitamin B12 on the size and growth of Euglena gracilis. J. Protozool., 9:336-339, 1962.

26. Epstein, S. S. and Timmis, G. M. Effect of Vitamin B12 antagonists and other compounds on the C1300 tumor.

Biochem. Pharmacol., 11:743-746, 1962.

27. Epstein, S. S. and Timmis, G. M. Simple antimetabolites of Vitamin B12. J. Protozool., 10:63-73, 1963.

28. Epstein, S. S., et al. The photodynamic effect of the carcinogen 3,4-benzpyrene on Paramecium caudatum. Cancer Res., 23:35-44, 1963.

29. Epstein, S. S., et al. Photodynamic bioassay of benzo(a)pyrene using Paramecium caudatum. J. Nat. Cancer Inst., 31:163-168, 1963.

30. Epstein, S. S., et al. A photodynamic bioassay of atmospheric pollutants. Proc. Amer. Assoc. Cancer Res., 4(1):18, 1963.

31. Epstein, S. S. Photodynamic activity of polycyclic hydrocarbon carcinogens. Acta Unio Internat. Contra Cancrum, 19:3/4, 599-601, 1963.

32. Epstein, S. S., et al. Photodynamic bioassay of polycyclic air pollutants. A.M.A. Arch. Env. Health, 7:531-537, 1963.

33. Small, M., Jones, H., and Epstein, S. S. Photodynamic activity of polycyclic compounds. Fed. Proc., 22:316, 1963.

34. Epstein, S. S., et al. On the association between photodynamic and carcinogenic activities in polycyclic compounds. Cancer Res., 24:855-862, 1964.

35. Foley, G. E. and Epstein, S. S. Cell culture and cancer chemotherapy.

In "Advances in Chemotherapy,"

1:1964, Academic Press, New York.

36. Epstein, S. S., et al. Charge-transfer complex formation, carcinogenicity and photodynamic activity in polycyclic compounds. Nature, 204:750-754, 1964.

37. Epstein, S. S., et al. Charge-transfer complex formation, carcinogenicity and photodynamic activity in polycyclic compounds. Fed. Proc., 232:287, 1964.

38. Epstein, S. S. Photoactivation of polynuclear hydrocarbons. A.M.A. Arch. Env. Health, 10:233-239, 1965.

39. Epstein, S. S., et al. Photodynamic bioassay of polycyclic atmospheric pollutants. J. Air Poll. Control Assoc., 15:174-176, 1965.

40. Epstein, S. S. A simple photodynamic assay for polycyclic atmospheric pollutants. World Health Organization Report, WHO/EBL/51, 1965.

41. Epstein, S. S., et al. A simple bioassay for antioxidants based on protection of Tetrahymena pyriformis from the photodynamic toxicity of benzo(a)pyrene. Nature, 208:655-658, 1965.

42. Small, M., Brickman, E., and Epstein, S. S. Uptake of polycyclic compounds by phagotropic protozoan. Fed. Proc., 24:684, 1965.

43. Epstein, S. S., et al. A simple bioassay for antioxidants. Fed. Proc., 24:623, 1965.

44. Epstein, S. S. Bioassay for polycyclic atmospheric pollutants and for antioxidants based on photodynamic response of protozoa. Abstract from Second International Conference on Protozoology, London. Reprinted from Excerpta Medica International Congress, Series 91, August, 1965.

45. Epstein, S. S. The lung as a transplant site for malignant tumors in rodents. Cancer, 19:454-457, 1966.

46. Epstein, S. S. and Joshi, S. R. Obstructive renal failure in random-bred Swiss mice. Fed. Proc., 25:237, 1966.

47. Epstein, S. S., et al. Interactions between antioxidant and photosensitizer in the photodynamic bioassay for antioxidants. Life Sciences, 5:783-793, 1966.

48. Epstein, S. S., et al. An exploratory investigation on the inhibition of selected photosensitizers by agents of varying antioxidant activity. Rad. Res., 28:322-335, 1966.

49. Epstein, S. S. and Tabor, F. B. Photosensitizing compounds in extracts of USA drinking water. Science, 154(3746):261-263, 1966.

50. Epstein, S. S. Two sensitive tests for carcinogens in the air. J. Air Poll. Control Assoc., 16(10):545-546, 1966.

51. Epstein, S. S., et al. Carcinogenicity of organic particulate pollutants in urban air after administration of trace quantities to neonatal mice. Nature, 212:1305-1307, 1966.

52. Small, A., Mantel, N., and Epstein, S. S. The role of cell-uptake of polycyclic compounds in photodynamic injury of Tetrahymena pyriformis. Exp. Cell Res., 45:206-217, 1967.

53. Epstein, S. S., et al. The null effect of antioxidants on the carcinogenicity of 3,4,9,10-dibenzpyrene to mice. Life Sci., 6:225-233, 1967.

54. Epstein, S. S. and Niskanen, E. E. Effects of Tween 60 on benzo(a)pyrene uptake by Tetrahymena pyriformis. Exp. Cell Res., 46:211-234, 1967.

55. Epstein, S. S., et al. The synergistic toxicity and carcinogenicity of Freons and piperonyl butoxide. Nature, 214:526-528, 1967.

56. Epstein, S. S., et al. Cytotoxicity of antioxidants to Tetrahymena pyriformis. J. Protozool., 14:238-244, 1967.

57. Nagata, C., Fujii, K., and Epstein, S. S. Photodynamic activity of 4-nitroquinoline-1-oxide and related compounds. Nature, 215:972-973, 1967.

58. Epstein, S. S., et al. Hepatocarcinogenicity of griseofulvin following parenteral administration to infant mice. Cancer Res., 27:1900-1906, 1967.

59. Epstein, S. S., et al. Carcinogenicity of the herbicide maleic hydrazide. Nature, 215:1388-1390, 1967.

60. Epstein, S. S. Carcinogenicity of organic extracts of atmospheric pollutants. J. Air Poll. Control Assoc., 17:728-729, 1967.

61. Epstein, S. S., et al. Enhancement by piperonyl butoxide of acute toxicity due to Freons, benzo(a)pyrene, and griseofulvin in infant mice. Toxicol. Appl. Pharmacol., 11:442-448, 1967.

62. McCarthy, R. E. and Epstein, S. S. Cytochemical and cytogenetic effects of maleic hydrazide on cultured mammalian cells. Life Sci., 7:1-6, 1968.

63. Epstein, S. S., et al. Photodynamic assay of neutral sub-fractions of organic extracts of particulate atmospheric pollutants. Env. Sci. Tech., 2:132-141, 1968.

64. Epstein, S. S. and Mantel, N. Hepatocarcinogenicity of maleic hydrazide following parenteral administration to infant Swiss mice. Internat. J. Cancer, 3:325-335, 1968.

65. Rondia, D. and Epstein, S. S. The effect of antioxidants on photodecomposition of benzo(a)pyrene. Life Sci., 7:513-518, 1968.

66. Epstein, S. S. Carcinogenicity of tetraethyl lead. Experientia, 24:580, 1968.

67. Epstein, S. S. and Shafner, H. Use of mammals in a practical screening test for chemical mutagens in the human environment. Nature, 219:385-387, 1968.

68. Jaffe, J., Fujii, K., Sengupta, M., Guerin, H., and Epstein, S. S. In vivo inhibition of mouse liver microsomal hydroxylating systems by methylene-dioxyphenyl insecticidal synergists and related compounds. Life Sci., 7:1051-1062, 1963.

69. Epstein, S. S. Irradiated Foods. Science, 161:739, 1968.

70. Fujii, K., Jaffe, H., and Epstein, S. S. Factors influencing the hexobarbital sleeping time and zoxazolamine paralysis time in mice. Toxicol. Appl. Pharmacol., 13:431-438, 1968.

71. Epstein, S. S. and Saporoschetz, I. B. On the association between lysogeny and carcinogenicity in nitroquinolines.

Experientia, 24:1245-58, 1968.

72. Jaffe, H., Fujii, K., Sengupta, M., Guerin, H., and Epstein, S. S. The bi-modal effect of piperonyl butoxide on o- and p-hydorxylation of biphenyl by mouse liver microsomes. Biochem. Pharmacol., 18:1045-1051, 1969.

73. Pagnatto, L. D. and Epstein, S. S. The effects of antioxidants on ozone toxicity in mice. Experientia, 25:703-704, 1969.

74. Epstein, S. S. A catch-all toxicological screen. Experientia, 25:617-618, 1969.

75. Epstein, S. S. and St. Pierre, J. S. Mutagenicity in yeast of nitroquinolines and related compounds.

Toxicol. Appl. Pharmacol., 15:451-460, 1969.

76. Epstein, S. S. Introduction to symposia on toxicologic and epidemiologic bases for air quality criteria. J. Air Pollution Control Assoc., 19:629-630, 1969.

77. Epstein, S. S. Chemical hazards in the human environment. Ca-A Cancer Journal for Clinicians, 19:277-281, 1969.

78. Epstein, S. S. Biological approaches to estimation of environment hazards. Drug Information Bulletin, 3:150-152, 1969.

79. Epstein, S. S., et al. Cyclamate ban. Science, 166:1575, 1969.

80. Lijinsky, W. and Epstein, S. S. Nitrosamines as environmental carcinogens. Nature, 225:21-23, 1970.

81. Epstein, S. S., et al. Carcinogenicity testing of food additives and antioxidants by parenteral administration to infant Swiss mice. Toxicol. Appl. Pharmacol., 16:321-334, 1970.

82. Fujii, K., Jaffe, H., Bishop, Y., Arnold, E., Mackintosh, D., and Epstein, S. S. Structure-activity relations for methylenedioxyphenyl and related compounds and hepatic microsomal enzyme functions, as measured by prolongation of hexobarbital narcosis and zoxazolamine paralysis in mice.

Toxicol. Appl. Pharmacol., 16:482-494, 1970.

83. Epstein, S. S., et al. Abnormal zygote development in mice after paternal exposure to a chemical mutagen. Nature, 225:1260-1261, 1970.

84. Epstein, S. S. and Lederberg, J. Chronic non-psychiatric hazards of drugs of abuse. Science, 168:507-509, 1970.

85. Epstein, S. S., et al. The mutagenicity of trimethyl phosphate in mice. Science, 168:584-586, 1970.

86. Mailing, H. V., Wassom, J. S. and Epstein, S. S. Mercury in our environment. Environmental Mutagen Society Newsletter, 3:7-9, 1970.

87. Epstein, S. S., et al. Mutagenic and antifertility effects of TEPA and METEPA in mice. Toxicol. Appl. Pharmacol., 17:23-40, 1970.

88. Epstein, S. S., et al. The failure of caffeine to induce mutagenic effects or to synergize the effects of known mutagens in mice. Fd. Cosmet. Toxicol., 8:381-401, 1970.

89. Epstein, S. S. A family likeness: 2,4,5-T and 2,4-D. Environment, 12:16-25, 1970.

90. Epstein, S. S. Mutagenitatsprufung in der Toxikologie. Unschau, 15:475-476, 1970.

91. Epstein, S. S., et al. Effects of methylenedioxyphenyl insecticidal synergists in vitro on hydroxylations of biphenyl by mouse liver microsomes. Biochem. Pharmacol., 19:2605-2607, 1970.

92. Joshi, S. R., Page, E. C., Arnold, E., Bishop, Y., and Epstein, S. S. Fertilization and early embryonic development subsequent to mating with TEPA-treated male mice. Genetics, 65:483-494, 1970.

93. Epstein, S. S. and Fujii, K. Synergism in carcinogenesis with particular reference to synergistic effects of piperonyl butoxide and related insecticidal synergists. Chapter, pp. 21-42. In, Chemical Tumor Problems. Nakahara, W., ed. Pub. Japanese Society for the Promotion of Science, Tokyo, Japan, 1970.

94. Epstein, S. S. I. Adverse biological effects due to chemical pollutants: General Principles. II. Potential carcinogenicity, mutagenicity and teratogenicity due to community air pollutants. Appendix M. pp. 1-54. Project Clean Air. Task Force Assessments. Vol. 2. Project Clean Air, Regents of the Univ. of California, Sept. 1, 1970.

95. Epstein, S. S. The failure of caffeine to induce mutagenic effects or to synergize the effects of known mutagens in mice. Chapter 25, pp. 404-419. In, Chemical Mutagens, ed. Vogel, F., and Rohrborn, G., Publ. Springer-Verlag, Berlin, Heidelberg, New York, 1970.

96. Friedman, M. and Epstein, S. S. Stability of piperonyl butoxide. Toxicol. Appl. Pharmacol., 17:810-812, 1970.

97. Epstein, S. S. NTA. Environment, 12:2-11, 1970.

98. Epstein, S. S. Control of chemical pollutants. Nature, 228:816-819, 1970.

99. Bateman, A. and Epstein, S. S. Dominant lethal mutations in mammals. Chapter in, Environmental Chemical Mutagens. Hollaender, A., ed., Plenum Publishing Co., New York, 1971.

100. Alam, B. S., Saporoschetz, I. B., and Epstein, S. S. Formation of N-nitrosopiperidine and sodium nitrite in the stomach and the isolated intestinal loop of the rat. Nature, 232:116-118, 1971.

101. Epstein, S. S., et al. Sterility and semi-sterility in male progeny of male mice treated with the chemical mutagen TEPA. Toxicol. Appl. Pharmacol., 19:134-146, 1971.

102. Epstein, S. S., et al. Bioassay for antioxidants based on protection of isolated rat liver mitochondria against the photodynamic toxicity of benzo(a)pyrene. Fd. Cosmet. Toxicol., 9:367-377, 1971.

103. Epstein, S. S., et al. On the association between photodynamic and enzyme-inducing activities in polycyclic compounds. Cancer Res., 13:1087-1094, 1971.

104. Alam, B. S., Saporoschetz, I. B., and Epstein, S. S. The synthesis of nitrosopiperidine from nitrate and piperidine in the stomach and small intestine and in isolated gastric contents of the rat. Nature, 232:199-200, 1971.

105. Epstein, S. S. and Rohrborn, G. Recommended procedures for testing genetic hazards due to chemicals, based on the induction of dominant lethal mutations in mammals. Nature, 230:459-460, 1971.

106. Epstein, S. S., et al. Eye on our Defenses. Environment, 13:43-47, 1971.

107. Friedman, M. A., Millar, G., McEvoy, A., and Epstein, S. S. Rapid and simplified method for liquid scintillation counting of radioactive proteins utilizing aquasol. Anal. Chem., 43:780, 1971.

108. Bishop, Y., Fujii, K., Arnold, E., and Epstein, S. S. Censored distribution technique in analysis of toxicological data. Experientia, 27:1056-1059, 1971.

109. Asahina, S., Friedman, M., Arnold, E., Millar, G., Mishkin, M., and Epstein, S. S. Acute synergistic toxicity and hepatic necrosis following oral administration of sodium nitrite and secondary amines to mice. Cancer Res., 31:1201-1205, 1971.

110. Friedman, M. A., Sengupta, M., Arnold, E., Bishop, Y., and Epstein, S. S. Additive and synergistic inhibition of mammalian microsomal enzyme functions by piperonyl butoxide, safrole and other methylenedioxyphenyl derivatives. Experientia, 27:1052-1054, 1971.

111. Adler, I. D., Ramarao, G., and Epstein, S. S. In vivo cytogenetic effects of trimethylphosphate and of TEPA on bone marrow cells of male rats. Mutation Res., 13:263-273, 1971.

112. Epstein, S. S. Environmental pathology: A review. Am. J. Path., 66:352-374, 1972.

113. Friedman, M. A., Sengupta, M., and Epstein, S. S. Paradoxical effects of piperonyl butoxide on the kinetics of mouse liver microsomal enzyme activity. Toxicol. Appl. Pharmacol., 21:419-427, 1972.

114. Epstein, S. S. Information requirements for determining the benefit-risk spectrum. In, Perspectives on Benefit-risk Decision Making, pp. 50-62. Committee on Public Engineering Policy, National Academy of Engineering, Washington, D. C., 1972.

115. Epstein, S. S. Identification of hazards in the environment: Introductory remarks. In, Environment and Cancer, pp. 56-68. Williams and Wilkins Pub. Co., Baltimore, 1972.

116. Friedman, M. A., Millar, G., Sengupta, M., and Epstein, S. S. Inhibition of mouse liver protein and nuclear RNA synthesis following combined oral treatment with sodium nitrite and dimethylamine or methylamine or methylbenzylamine. Experientia, 28:2-22, 1972.

117. Epstein, S. S. Toxicological and environmental implications on the use of nitrilotriacetic acid as a detergent builder - I. Int. J. Environ. Studies, 2:291-300, 1972.

118. Toxicological and environmental implications on the use of nitrilotriacetic as a detergent builder - II.

Int. J. Environ. Studies, 3:13-21, 1972.

119. Friedman, M. A., Green, E. J., and Epstein, S. S. Rapid gastric absorption of sodium nitrite in mice. J. Pharm. Sci., 61:1492-1494, 1972.

120. Epstein, S. S., et al. Detection of chemical mutagens by the dominant lethal assay in the mouse. Toxicol. Appl. Pharmacol., 23:288-325, 1972.

121. Asahina, S., Andrea, J., Carmel, A., Arnold, E., Bishop, Y., Joshi, S., Coffin, D., and Epstein, S. S. Carcinogenicity of organic fractions of particulate atmospheric pollutants in New York City following parenteral administration to infant mice. Cancer research, 32:2263-2268, 1972.

122. Epstein, S. S. Teratological hazards due to Phenoxy Herbicides and Dioxin Contaminants. Chap. 12, pp. 708-729. In, Pollution: Engineering and Scientific Solutions. Barrekette, E. S., ed., Pub. Plenum Publ. Co., New York, 1972.

123. Epstein, S. S. In vivo studies on interactions between secondary amines and nitrites or nitrates, pp. 109-115. In, N-Nitroso Compounds. Analysis and Formation. International Agency for Research on Cancer, Lyon, France. Scientific Publication No. 3, 1972.

124. Friedman, M. A., Millar, G. N., and Epstein, S. S. Acute dose-dependent inhibition of liver nuclear RNA synthesis and methylation of guanine following oral administration of sodium nitrite and dimethylamine to mice. Int. J. Environ. Studies, 4:219-222, 1973.

125. Lavappa, K. S., Fu, M. M., Sing, M., Beyer, R. D., and Epstein, S. S. Banding patterns of chromosomes in bone marrow cells of the Chinese hamster as revealed by acetic-saline-Giemsa, urea and trypsin techniques.

Lab. Animal Sci., 23:546-550, 1973.

126. Lavappa, K. S., Yerganian, G., and Epstein, S. S. Autosomal heteromorphism in the Armenian hamster. Genetics, 74:S151, 1973.

127. Epstein, S. S. The Delaney Amendment. Ecologist, 3:420-431, 1973.

128. Epstein, S. S. The Delaney Amendment. Preventive Med., 2:140-149, 1973.

129. Epstein, S. S. Environment and Teratogenesis. Chapter 8, pp. 105-113. In, Pathobiology of Development. Perrin, E. V. and Finegold, M. J., eds., Pub. Williams and Wilkins Co., Baltimore, 1973.

130. Joshi, S. R., Bishop, Y., and Epstein, S. S. Reduced fertility in mice following treatment with Niridazole. Experientia, 29:1253-1255, 1973.

131. Epstein, S. S. Use of the dominant lethal test to detect genetic activity of environmental chemicals. Environ. Health Perspec., 6:23-26, 1973.

132. Fine, D. H., Rufeh, F., Lieb, D., and Epstein, S. S. A possible nitrogen oxide-nitrosamine cancer link. Bull. Environ. Contam. Toxicol., 11:18-19, 1974.

133. Epstein, S. S. Definition of risk: Priority for safety, pp. 241-248. In, Environmental Quality and Food Supply. White, P. L., ed., Futura Publ. Co., Inc., 1974.

134. Epstein, S. S. Chronic biological hazards due to chemicals. In, Birth Defects and Fetal Development. Chapter 9, pp. 136-166. Moghissi, H., ed., C. C. Thomas Publ., Springfield, IL, 1974.

135. Alarif, A. and Epstein, S. S. Chemical synthesis of methyl C14 and H3 labeled N-methylnitrosourethane. J. Labeled Comp., 10:161-164, 1974.

136. Epstein, S. S. Introductory Remarks to Sessions on "Mutagens in the Biosphere." First International Conference on Environmental Mutagens. Asilomar, Calif., 1973. Mutation Res., 26:219-223, 1974.

137. Epstein, S. S. The carcinogenicity of Dieldrin. resources at Hearings on Aldrin/Dieldrin, Environmental Protection Agency and Environmental Defense Fund vs. Shell. Cancellation Hearings, March, 1974: Suspension Hearings, Sept., 1974.

138. Epstein, S. S. Environmental determinants of human cancer. Cancer Res., 34:2425-2435, 1974.

139. Epstein, S. S. Multiple factors in carcinogenesis. Environ. Health Perspec., 9:319-324, 1974.

140. Amacher, D. D., Alarif, A., and Epstein, S. S. The effects of ingested chrysotile on DNA synthesis in the gastrointestinal tract and liver of the rat. Environ. Health Perspec., 9:319-324, 1974.

141. Alarif, A. and Epstein, S. S. The uptake and metabolism of 14C-labeled nitrosomethyl urethane and methyinitrosourea in guinea pigs and their in vitro metabolism in the guinea pig and human pancreas. International Agency for Research of Cancer. Lyon, France, 215-219, 1974.

142. Billmaier, D., Yee, T., Allen, N., Craft, R., Williams, N., Fontaine, R., and Epstein, S. S. Peripheral neuropathy in a coated fabrics plant. J. Occupational Medicine, 16:655-671, 1974.

143. Epstein, S. S. and Hattis, D. Regulatory aspects of occupational carcinogens. Proceedings XI International Cancer Congress. Florence, October 20-26, 1974. In, Vol. 3, Cancer Epidemiology, Environmental Factors, 1974.

144. Epstein, S. S. Carcinogens in industry: needed studies. In, the New Multinational Health Hazards, pp. 172-188, Proceedings of the ICF International Occupational Health Conference, Geneva, October 20-30, 1974.

145. Legator, M. S. and Epstein, S. S. Testing for chemically-induced mutations. Chapter 9, Environmental Problems on Medicine, Ed., McKee, W. Published by C. C. Thomas, Springfield, IL, 1974.

146. Epstein, S. S. and Hattis, D. Adverse health effects and chemical pollutants of the environment. Chapter 8. In Environment: Resources, Pollution and Society, 2nd edition. Ed., Murdoch, W. N., Publisher, Sinauer Associates, 1975.

147. Epstein, S. S. Impact of mobile emissions control. The public interest overview. Conference on Health Consequences of Environmental Controls. Environmental Health Perspectives, 10:173-179, 1975.

148. Hasumi, K., Iqbal, Z. M., Alarif, A., and Epstein, S. S. DNA repair synthesis following exposure of guinea pig pancreatic slices to methyl-N-nitrosourethane in vitro. Experientia, 31:467, 1975.

149. Epstein, S. S. The carcinogenicity of Dieldrin. I. The Science of the Total Environment, 4:1-52, 1975.

150. Epstein, S. S. The carcinogenicity of Dieldrin. II. The Science of the Total Environment, 4:205-217, 1975.

151. Fine, D. H., Rounbehler, D. P., Huffman, F., and Epstein, S. S. Analysis of volatile N-nitroso compounds in drinking water at the part per trillion level. Bull. Environ. Contam. Toxicol., 14:404-408, 1975.

152. Hasumi, K., Wilber, J. H., Berkowitz, J., Wilber, R. G., and Epstein, S. S. Pre- and post-natal toxicity induced in guinea pigs by N-nitrosomethyl urea. Teratology, 12:105-110, 1975.

153. Fine, D. H., Rounbehler, D. P., Belcher, N. M., and Epstein, S. S.

N-Nitroso Compounds in the Environment. International Conference on Environmental Sensing and Assessment. Las Vegas, September 14-19, 1975.

154. Amacher, D. E., Alarif, A., and Epstein, S. S. The dose-dependent effect of ingested chrysotile on DNA synthesis in the gastrointestinal tract, liver and pancreas of the rat. Environ. Res., 10:208-216, 1975.

155. Lavappa, K. S., Fu, M. M., and Epstein, S. S. Cytogenetic studies on chrysotile asbestos. Environ. Res., 10:165-173, 1975.

156. Page, T., Harris, R. H., and Epstein, S. S. Drinking water and cancer mortality in Louisiana. Science, 193:55-57, 1976.

157. Hasumi, K., Iqbal, Z. M., and Epstein, S. S. DNA repair synthesis in guinea pig slices following in vitro exposure to nitrosomethylurethane. Chem.-Biol. Interactions, 13:279-286, 1976.

158. Epstein, S. S. and Varnes, M. The short-term effects of ingested chrysotile asbestos on DNA synthesis in the pancreas and other organs of a primate. Experientia, 32:602-604, 1976.

159. Fine, D. H., Rounbehler, D. P., Belcher, N. M., and Epstein, S. S.

N-nitroso compounds: Detection in ambient air. Science, 192:1328-1330, 1976.

160. Epstein, S. S. Potential Carcinogenic Hazards Due to Contaminated Drinking Water. Proceedings of the International Conference on Biological Control of Water Pollution, pp. 73-84, Eds., Tourbier, J. and Pierson, R. W., University of Pennsylvania Press, 1976.

161. Iqbal, Z. M., Majdan, M., and Epstein, S. S. Evidence of repair of DNA damage induced by 4-hydroxyaminoquinoline-1-oxide in guinea pig pancreatic slices in vitro. Cancer Res., 36:1108-1113, 1976.

162. Epstein, S. S. Aldrin and dieldrin: Suspension based on environmental evidence and evaluation of societal needs. Conference on Occupational Carcinogenesis, March 24, 1976. New York Academy of Sciences, 271:187-195, 1976.

163. Epstein, S. S. The political and economic basis of cancer. Technology Review, 79:34-43, 1976.

164. Iqbal, Z. M. and Epstein, S. S. Effects of N-methyl-N-nitrosourethane on DNA synthesis in the guinea pig pancreas. Chem. Biol. Interactions, 15:131-137, 1976.

165. Epstein, S. S. The carcinogenicity of heptachlor and chlordane. The Science of the Total Environment, 6:103-104, 1976.

166. Iqbal, Z. M. and Epstein, S. S. Kinetics of DNA repair synthesis in guinea pig pancreatic slices following in vitro exposure to N-methyl-N-nitrosourethane. Experientia, 32:1055-1056, 1976.

167. Iqbal, Z. M. and Epstein, S. S. DNA repair synthesis in guinea pig pancreas following exposure to nitrosomethylurethane. International Agency for Cancer Research, WHO, Publication No. 141, pp. 411-424, Lyon, France, 1976.

168. Epstein, S. S. et al. Pre-natal and post-natal toxicity induced in guinea pigs by nitrosomethylurea. International Agency for Cancer Research, WHO, Publication No. 14, pp. 435-442, Lyon, France, 1976.

169. Fine, D. H., Rounbehler, D. P., Belcher, N. M., and Epstein, S. S.

N-nitroso compounds in air and water. International Agency for Cancer Research, WHO, Publication No. 14, pp. 401-408, Lyon, France, 1976.

170. Epstein, S. S. Developing Health Policies and Standards; Responsibility of the scientist in developing and interpreting "Public Interest" viewpoints. LASL Third Life Sciences Symposium, Los Alamos, New Mexico, October 15-17, 1975, pp.

42-50. In "Impact of Energy Production in Human Health," eds. E. C. Anderson and E. M. Sullivan, Energy Res. and Development Adm., 1976.

171. Gage, K. and Epstein, S. S. The federal advisory committee system. Environmental Law Reporter, 7:50001-50002, 1977.

172. Epstein, S. S. Cancer and the environment. Bull. Atomic Scientists, 33(3):22-30, 1977.

173. Iqbal, Z. M., Varnes, M. E., Yoshida, A., and Epstein, S. S. Metabolism of benzo(a)pyrene by guinea pig pancreatic microsomes. Cancer Res., 37:1011-1015, 1977.

174. Fine, D. H., Rounbehler, D. P., Ross, R., Song, L., Silvergleid, A., Iqbal,

Z. M., and Epstein, S. S. Quantitation of dimethylnitrosamine in the whole mouse following biosynthesis from trace levels of precursors. Science, 197:917-918, 1977.

175. Epstein, S. S. The case for a Consumer Protection Agency. Bull. Atomic Scientist, 33(7):6-7, 1977.

176. Epstein, S. S. et al. Protection by antioxidants against the toxicity of ozone to microbial systems. Environmental Res., 14:187-193, 1977.

177. Yoshida, Q., Iqbal, Z. M., and Epstein, S. S. Hepatocarcinogenic effects of

N-methyl-N-nitrosourea in guinea pigs. Cancer Res., 37:4043-4048, 1977.

178. Epstein, S. S. The carcinogenicity of organochlorine pesticides, pp. 243-265. In "Origins of Human Cancer," eds. H. H. Hiatt, J. D. Watson, and

J. A. Winsten, Cold Spring Harbor Laboratory, 1977.

179. Epstein, S. S. Kepone: hazard evaluation. The Science of the Total Environment, 9:1-62, 1978.

180. Iqbal, Z. M. and Epstein, S. S. Evidence of DNA repair in the guinea pig pancreas in vivo and in vitro, following exposure to N-methyl-N-Nitrosourethane. Chem.-Biol. Interactions, 20:77-87, 1978.

181. Epstein, S. S. Polluted Data. The Sciences, 18:16-21, 1978.

182. Infante, P. F., Newton, W. A., and Epstein, S. S. Blood dyscrasias and childhood tumors following exposure to chlorinated hydrocarbon pesticides. Scand. J. Work Environment, 4:137-150, 1978.

183. Epstein, S. S. Carcinogenicity of a composite organic extract of urban particulate atmospheric pollutants following subcutaneous injection in infant mice. Environmental Res., 19:163-176, 1979.

184. Fujii, S. and Epstein, S. S. Effects of piperonyl butoxide on the toxicity and hepatocarcinogenicity of 2-acetylaminofluorene and 4-acetylaminobiphenyl, and their N-hydroxylated derivatives, following administration to newborn mice. Oncology, 36:105-112, 1979.

185. Iqbal, Z. M., Yoshida, A., and Epstein, S. S. Uptake and excretion of benzo(a)pyrene and its metabolites by the rat pancreas. Drug Metabolism and Disposition, 7:44-48, 1979.

186. Yoshida, A., Iqbal, Z. M., and Epstein, S. S. Spontaneous pancreatic islet cell tumors in guinea pigs. J. Comp. Pathol., 89:471-480, 1979.

187. Epstein, S. S. Cancer and inflation. The Ecologist, 9:236-246, 1979.

188. Epstein, S. S. Polluted data. The Ecologist, 9:264-268, 1979.

189. Epstein, S. S. The Polluters hit back. The Ecologist, 9:269-272, 1979.

190. Epstein, S. S. Information, requirements of the public. American Industrial Health Association Journal, pp. 48-54, December, 1979.

191. Epstein, S. S. Cancer, inflation and the failure to regulate. Technology Review, 82:42-53, 1979.

192. Epstein, S. S., et al. Geographic Distribution of Cancer in Illinois. Illinois Institute of Natural Resources, Document No. 79/40, December, 1979.

193. Iqbal, Z. M., Dahl, K., and Epstein, S. S. Role of nitrogen dioxide in the biosynthesis of nitrosamines in mice. Science, 207:1475-1477, 1980.

194. Whalley, C. E., Iqbal, Z. M., and Epstein, S. S. The separation of

N-nitroso-di-n-propylamine and its

B-oxidized carcinogenic metabolites by high pressure liquid chromatography. J. Liquid Chromat., 3:693-703, 1980.

195. Epstein, S. S. and Swartz, J. Fallacies of lifestyle cancer theories. Nature, 289:127-130, 1981.

196. Whalley, C. E., Iqbal, Z. M., and Epstein, S. S. In vivo and microsomal metabolism of the pancreatic carcinogen N-Nitrosobis(2-oxopropyl)amine by the Syrian golden hamster. Cancer Res., 41:482-486, 1981.

197. Iqbal, Z. M. and Epstein, S. S., et al. Kinetics of nitrosamine formation in mice following oral administration of trace-level precursors. International Agency for Research on Cancer (IARC), Proceeding of VIth International Symposium on N-Nitroso Compounds, Budapest, October

16-20, 1979, pp. 195-206, IARC Scientific Publication No. 31, Lyon, France, 1980.

198. Epstein, S. S., et al. In Vivo Nitrosation of Morpholine in Mice by Inhaled NO2. International Agency for Research on Cancer (IARC), Proceeding of VIth International Symposium of N-Nitroso Compounds, Budapest, October 16-20, 1979, pp. 195-206, IARC Scientific Publication No. 31, Lyon, France, 1980.

199. Epstein, S. S. "The Price We Pay for Progress: The Hazards of the Halogenated Hydrocarbons." Proceedings International Conference, "Chemistry-Man-Environment: Halogenated Hydrocarbons," Gottlieb Duttweiler Institute, Zurich, Switzerland, October 13-15, 1980.

200. Epstein, S. S. "The Politics of Cancer: The Costs of Failure to Regulate." Proceedings of the Warner-Lambert Science and Public Policy Colloquium, The University of Michigan, Collegiate Institute for Values and Science, November 1-2, 1980.

201. Epstein, S. S. The role of the scientist in toxic tort case preparation. Trial, 17:38-78, 1981.

202. Epstein, S. S. Focus on Food Safety: Evaluating Risk Measurements. Proceedings Fourth National Food Policy Conference. Community Nutrition Institute and Food Marketing Institute, pp. 48-57, Washington, D. C., April 7, 1981.

203. Iqbal, Z. M., Dahl, K., and Epstein, S. S. Biosynthesis of dimethylnitrosamine in dimethylamine-treated mice after exposure to nitrogen dioxide. J. Nat. Cancer Inst., 67:137-141, 1981.

204. Epstein, S. S. Surviving in the petrochemical age: Social and economic pressures needed to improve toxic waste disposal. Journal of Alternative Human Services, 7(5):18-24, 1981.

205. Epstein, S. S. It costs us all more not to regulate. In These Times, pp. 16-77, August 12-25, 1981.

206. Iqbal, Z. M. and Epstein, S. S. In vivo nitrosation of amines by inhaled nitrogen dioxide and inhalation biosynthesis of nitrosamines. International Agency for Research in Cancer (IARC), Scientific Publication, Proceedings of VIIth International Symposium on N-Nitroso Compounds, Tokyo, Japan. September 28 - October 1, 1981.

207. Swartz, J. B. and Epstein, S. S. Problems in assessing risks from occupational and environmental exposure to carcinogens, pp. 559-575. Banbury Report 9: Qualification of Occupational Cancer, Cold Spring Harbor Laboratory, 1981.

208. Epstein, S. S. Cost-benefit analysis: Inspired by rational economics or a protectionist philosophy. The Amicus Journal, 3(4):41-47, 1982.

209. Epstein, S. S. Public Health Concerns on the Proposed Alaska Petrochemical Complex. Proceedings of the VIIth Alaska Health Conference on Energy, Health and the Environment: The Health Impact of Petrochemical Development, Anchorage, Alaska, May 6-8, 1982.

210. Swartz, J. B., Riddiough, C. R., and Epstein, S. S. Analysis of carcinogenesis dose response data: Implications for carcinogenic risk assessment. Teratogenesis, Carcinogenesis and Mutagenesis, 2(2):179-204, 1982.

211. Epstein, S. S. The ideal solution: Options for hazardous wastes. The Amicus Journal, pp. 6-7, Spring, 1983.

212. Epstein, S. S. Agent Orange diseases: Problems of causality, burdens of proof and restitution. Trial, 19:91-99, 1983.

213. Epstein, S. S. Hazardous Waste Management. Hazardous Materials and Waste Management Magazine, Kutztown, PA, pp. 17-23, May/June, 1983.

214. Epstein, S. S. and Gofman, J. Irradiation of foods. Science, 223:1354, 1984.

215. Epstein, S. S. and Swartz, J. B. Cancer and diet: A rebuttal to B. Ames (Science, 221:1256-1264, 1983) Science, 224:660-667, 1984. (Endorsed by 16 co-signatories)

216. Dwyer, J. H. and Epstein, S. S. Cancer and Clinical Epidemiology: An Overview. Chapter 6, pp. 123-129. In, Herbicides in War, The Long-Term Ecological and Human Consequences, ed. A. H. Westing, Stockholm International Peace Research Institute, Stockholm, Sweden, 1984.

217. Epstein, S. S. The Toll of Chemical Warfare at Home: The Politics of Cancer, pp. 85-90. In, Issues '84, Dear Mr. President-Elect, eds. Green, M. and Siegal, J., The Democracy Project, New York, September 1984.

218. Epstein, S. S. Billions for cures, barely a cent to prevent. Environmental Action, pp. 10-11, November/December 1984.

219. Epstein, S. S. Environmental Issues in Medicine: A Dissenting View. In, Dissent in Medicine, ed. R. Mendelsohn, Contemporary Books, Chicago, Illinois, 1985.

220. Epstein, S. S. The environmental question: Beyond lifestyle change. Health and Medicine, 3:19-21, 1985.

221. Epstein, S. S. U.S. Veterans and Agent Orange. International symposium on the Long-term Ecological and Human Consequences of Chemical Warfare in Vietnam. Jan. 14, 1983, published in "Herbicides in War." Ed. A. H. Westing, Stockholm International Peace Research Institute, Taylor & Francis, London/Philadelphia, 1984.

222. Epstein, S. S. Natural products and cancer: A rebuttal to P. Abelson. In, Readers Forum, Remote Sensing of the Planet: Impact of Science on Society, UNESCO, France, September 1985.

223. Epstein, S. S. and Briggs, S. Silent spring in retrospect. Environmental Law Reporter, 17:10180-10184, 1987.

224. Epstein, S. S. Losing the war against cancer. The Ecologist, 17:91-101, 1987.

225. Epstein, S. S. Are we losing the war against cancer? Congressional Record, 133:E3449-E3454, 1987.

226. Epstein, S. S. and Ozonoff, D. Leukaemias and blood dyscrasias following exposure to chlordane and heptachlor. Carcinogenesis, Mutagenesis and Teratogenesis, 7:527-540, 1987.

227. Epstein, S. S. The politics of cancer. Multinational Monitor, 9(3):6-13, 1988.

228. Epstein, S. S. and Swartz, J. B. Carcinogenic risk estimation. Rebuttal to B. Ames (Science, 236:271, 1987) Science, 240:1043-1047, 1988. (Endorsed by 15 co-signatories)

229. Epstein, S. S. Carcinogenic Pesticides in Food and the Delaney Amendment. National Coalition Against Misuse of Pesticides, Annual Meeting. Washington, D. C., Keynote Address, March 18, 1989.

230. Epstein, S. S. The Externalized Public Health and Environmental Costs of Gasoline. National Conference on Octane and Oxygenated Fuels, San Francisco, March 22, 1989.

231. Epstein, S. S. Corporate crime: Can we trust industry-derived safety studies? The Ecologist, 19:23-30, 1989.

232. Epstein, S. S. The real cost of petrol. The Ecologist, 19:137-138, 1989.

233. Epstein, S. S. The chemical jungle: Today's beef industry. Multinational Monitor, 10(5):8-9, 1989.

234. Epstein, S. S. Potential health hazards of biosynthetic milk hormones. Report to the Food and Drug Administration, July 19, 1989.

235. Epstein, S. S. BST: The public health hazards. The Ecologist, 19:191-195, 1989.

236. Epstein, S. S. Losing the war against cancer: Who's to blame and what to do about it. International Journal of Health Services, 20:53-71, 1990.

237. Epstein, S. S. Potential public health hazards of biosynthetic milk hormones. International Journal of Health Services, 20:73-84, 1990.

238. Epstein, S. S. The chemical jungle: Today's beef industry. International Journal of Health Services, 20(2):277-280, 1990.

239. Epstein, S. S. Editorial misconduct in Science. International Journal of Health Services, 20(2):349-352, 1990.

240. Epstein, S. S. Corporate crime: Why we cannot trust industry-derived safety studies. International Journal of Health Services, 20(3):443-458, 1990.

241. Lashner, B. and Epstein, S. S. Industrial risk factors for colorectal cancer. International Journal of Health Services, 20(3):459-483, 1990.

242. Clapp, R. W., Commoner, B., Constable, J. D., Epstein, S. S., et al. Human Health Effects Associated with Exposure to Herbicides and/or Their Associated Contaminants, Chlorinated Dioxins. Report to the American Legion and Vietnam Veterans of American, April 1990.

243. Epstein, S. S. Questions and answers on synthetic bovine growth hormones. International Journal of Health Services, 20(4):573-582, 1990.

244. Lashner, B. and Epstein, S. S. Industrially related colorectal cancer: Eminently preventable. Chicago Medicine, 93(18):30-31, 1990.

245. Epstein, S. S. Summary public health perspectives on rBGH. National Institutes of Health, Technology Assessment Conference on Bovine Somatotropin. National Institutes of Health, December 5-7, 1990.

246. Epstein, S. S., et al. Losing the war against cancer: A need for public policy reforms. Int. J. Health Services, 22(3):455-469, 1992.

247. Epstein, S. S. The cancer war and its critics. Int. J. Health Services, 22(4):747-749, 1992.

248. Epstein, S. S. Profiting from cancer. The Ecologist, 22:233-240, 1992.

249. Fugh-Berman, A. and Epstein, S. S. Tamoxifen: Disease prevention or disease substitution? The Lancet, 340:1143-1145, 1992.

250. Fugh-Berman, A. and Epstein, S. S. Should healthy women take tamoxifen? New Eng. J. Med., 327:1596, 1992.

251. Epstein, S. S. Evaluation of the national cancer program and proposed reforms. Int. J. Health Services, 23(1):15-44, 1993.

252. Epstein, S. S. Evaluation of the national cancer program and proposed reforms. American J. Ind. Med., 24:109-133, 1993.

253. Fugh-Berman, A. and Epstein, S. S. Tamoxifen for breast cancer prevention. A cautionary review. Reviews on Endocrine-Related Cancer, 43:1-11, 1993.

254. Epstein, S. S. Breast Cancer and The Environment. The Ecologist, 23(5):192-193, 1993.

255. Epstein, S. S. Environmental pollutants as unrecognized causes of breast cancer. Int. J. Health Services, 24(1):145-150, 1994.

256. Swartz, J. B. and Epstein, S. S. What is responsible for the rise in lung cancer mortality? New Solutions pp. 62-70, Spring 1995.

257. Epstein, S. S. Response to criticisms of the September 1994, Los Angeles Times Guest Commentary on cancer risk of breast implants. Medical-Legal aspects of breast implants, Medical Monitor, Leader Publications, 3(2):7-8, 1995.

258. Epstein, S. S. Implants pose poorly recognized risks of breast cancer. Int. J. Occup. Med. Toxicol., 4(3):315-342, 1995.

259. Epstein, S. S. Unlabeled milk from cows treated with biosynthetic growth hormones: A case of regulatory abdication. Int. J. Health Services, 26(1):173-185, 1996.

260. Epstein, S. S. Avoidable toxins in condos: how to go green. Condo Lifestyles, 1(3):6-10, 1997.

261. Black, D. L., Fugate, M. E., and Epstein, S. S. Poly(ester) urethane foam covered Breast Implants: biodegradation and release of toluene diamines. Clinical Chemistry, In press, 1998.

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