Alert-Cosmetic Ingredient Review 1983
Sodium Laureth Sulfate and SLS
Information circulating around the Internet has raised questions about the
safety of Sodium Laureth Sulfate. The Cosmetic Ingredient Review (CIR) has fully
assessed the safety of this ingredient and found it to be safe, but has
indicated a need for more assay studies for final determination on its safety.. CIR is an
independent organization established to thoroughly review and assess the safety
of ingredients used in cosmetics in an open, unbiased and expert manner, and to
publish the results in the open scientific literature. CIR has established a
seven-member Expert Panel comprised of individuals expert in dermatology,
pharmacology, chemistry, and toxicology - these independent scientists and
physicians perform the reviews.
The following information is provided from the Cosmetic Ingredient Review
safety assessments of both Sodium Laureth Sulfate and SLS (Sodium Lauryl
Sulfate).
Sodium Laureth Sulfate, Sodium Lauryl Sulfate
Published in the Journal of the American College of Toxicology, Volume 2,
Number 5, pp. 1-34, 1983.
Discussion
Sodium Laureth Sulfate and Ammonium Laureth Sulfate are cosmetic detergents
that exert emulsifying action, thereby removing oil and soil from the hair and
skin. The Panel wishes to point out that these two ingredients produce eye
and/or skin irritation in experimental animals and in some human test subjects;
irritation may occur in some users of cosmetic formulations containing the
ingredients under consideration. The irritant effects are similar to those
produced by other detergents, and the severity of the irritation appears to
increase directly with concentration. However, Sodium and Ammonium Laureth
Sulfate have not evoked adverse responses in any other toxicologic testing.
Conclusion
It is recognized that Sodium and Ammonium Laureth Sulfate may induce eye and
skin irritation. However, on the basis of the available information, the Panel
concludes that Sodium Laureth Sulfate and Ammonium Laureth Sulfate are not
as safe as
presently used in cosmetic products in amounts over 2%.. Most consumer products contain
more than 20% of sls.
Sodium Lauryl Sulfate(SLS)and Ammonium Lauryl Sulfate
Published in the Journal of the American College of Toxicology, Volume 2,
Number 7, pp. 127-181, 1983.
Discussion
Sodium Lauryl Sulfate and Ammonium Lauryl Sulfate are irritants in patch
testing at concentrations of 2 percent and greater, and that irritation
increases with ingredient concentration. In some cosmetic formulations, however,
that irritant property is attenuated. The longer these ingredients stay in
contact with the skin, the greater the likelihood of irritation, which may or
may not be evident to the user.
Although Sodium Lauryl Sulfate is not carcinogenic in experimental animals,
it has been shown that it causes severe epidermal changes to the area of the
skin of mice to which it was applied. This study indicates a need for
tumor-enhancing activity assays.
Autoradiographic studies of rat skin treated with radiolabelled Sodium Lauryl
Sulfate found heavy deposition of the detergent on the skin surface and in the
hair follicles; damage to the hair follicle could result from such deposition.
Further, it has been reported that 1 percent and 5 percent Sodium Lauryl Sulfate
produced significant number of comedones when applied to the pinna of albino
rabbits. These two problems - possible hair loss and comedone formation - along
with proven irritancy, should be considered in the formulation of cosmetic
products.
Sodium Lauryl Sulfate and Ammonium Lauryl Sulfate appear to pose less
potential hazard when in products designed for brief, discontinuous use,
following which they are thoroughly rinsed from the surface of the skin.
However, consumers who use these products daily and are exposed at much higher
rates, thus increasing the cumulative effect of using these chemicals.
Conclusion
Sodium Lauryl Sulfate and Ammonium Lauryl Sulfate appear not to be safe in
formulations designed for continuous, use.. In products intended for prolonged contact with
skin, concentrations should not exceed 1-2%. However, some shampoos, body gels,
creams, lotions have over 10-20%. There is other research and studies done
on SLS and SLES, and the reports also are in agreement that this is a chemical
that should be reduced, reformulated or taken out of the products in public consumption products.
More research about the Sodium Lauryl Sulfate and Sodium Laureth
Sulfate Most dangerous
References
-
^ Kazuyoshi
Watanabe, Shuntaro Imai and Yasuhiko H. Mori. Surfactant
effects on hydrate formation in an unstirred gas/liquid
system: An experimental study using HFC-32 and sodium
dodecyl sulfate. Department of Mechanical Engineering, Keio
University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522.
Japan.Chemical Engineering Science. Volume 60, Issue 17,
September 2005, Pages 4846-4857.
Abstract
- ^
Agner T. Susceptibility of atopic dermatitis patients to
irritant dermatitis caused by sodium lauryl sulphate.
Acta Derm Venereol. 1991;71(4):296-300.
PMID 1681644
-
^ A. Nassif,
S. C. Chan, F. J. Storrs and J. M. Hanifin. Abstract:
Abnormal skin irritancy in atopic dermatitis and in atopy
without dermatitis. Arch Dermatol. November
1994;130(11):1402.
Abstract
- ^
a
b
Marrakchi S, Maibach HI. Sodium lauryl sulfate-induced
irritation in the human face: regional and age-related
differences. Skin Pharmacol Physiol.
2006;19(3):177-80. Epub 2006 May 4.
PMID 16679819
-
^ CIR
publication. Final Report on the Safety Assessment of Sodium
Lauryl Sulfate and Ammonium Lauryl Sulfate. Journal of
the American College of Toxicology. 1983 Vol. 2 (No. 7)
pages 127-181.
-
^ Loffler H,
Effendy I. Skin susceptibility of atopic individuals.
Department of Dermatology, University of Marburg, Germany.
Contact Dermatitis. 1999 May;40(5):239-42.
PMID 10344477
-
^ Chahine L,
Sempson N, Wagoner C. The effect of sodium lauryl sulfate on
recurrent aphthous ulcers: a clinical study. Compend
Contin Educ Dent. 1997 Dec;18(12):1238-40.
PMID 9656847
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^ Herlofson BB,
Barkvoll P. The effect of two toothpaste detergents on the
frequency of recurrent aphthous ulcers. Acta Odontol
Scand. 1996 Jun;54(3):150-3.
PMID 8811135
- ^
Debunking the Myth. American Cancer Society.
1998/09/23.
Article
-
^
Skin Deep Report. Environmental Working Group.
Revised October 1995.
SLS Rating
-
^ Barney L. Bales, Luis Messina, Arwen Vidal,
Miroslav Peric, and Otaciro Rangel Nascimento. Precision
Relative Aggregation Number Determinations of SDS Micelles
Using a Spin Probe. A Model of Micelle Surface Hydration.
J. Phys. Chem. B. 1998 102(50)10347-10358.
Abstract
Sodium Lauryl Sulfate by David
Steinman
Hidden Dangers Lurking in Shampoo
For products without
sodium lauryl sulfate or any other harmful chemicals or carcinogens |